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January 5, 2022


Dr. Zhu has shown that PIEZO1 mediates a mechanothrombotic pathway in diabetes. An ion channel complicates clots in patients with diabetes, leaving them with an increased risk for thrombosis.

September 22, 2021


Impossible to do large reverse genetic screens in vivo? Not according to the team of Dr. Randall Peterson at the University of Utah! Congrats to his team and especially Saba for this amazing study! We are excited we were able to contribute to this one! 

May 11, 2021


Check out Shinichi’s Nature Communications paper on automated detection of cardiac amyloidosis using Artificial Intelligence offering a glimpse into the future of detection of rare cardiac diseases.

April 27, 2021


One of our favorite proteins strikes again! Out now in Circulation Research: a new role for Prdm16 in arterial endothelial maintenance in ischemic conditions.

October 22, 2020


The Koren and MacRae lab teamed up to demonstrate that LITAF determines QT interval variation by regulating cardiac Ca2+ and Na+ homeostasis.

November 16, 2019


MacRae lab provides new insights into the pathophysiology of cardiac arrhythmias! Check out our latest Circulation paper on how we used both human ES cells and zebrafish to explore potential new avenues to treat atrial fibrillation.