Shane Wright

I am currently a 3rd year biomedical engineering PhD candidate at Boston University pursuing my thesis in the MacRae lab under the co-advising of Ahmad Khalil. My research is focused on the adverse effects of red blood cell donations on innate immunity and the coagulation cascade. Using high-throughput clotting techniques and a variety of functional assays, I hope to gain insight into the active mechanisms by which transfused red blood cell interactions can cause certain patients to be at high risk for postoperative thrombosis. The goal is to then parlay this knowledge with my engineering skills to provide novel solutions that address these issues. I am also investigating the incorporation of novel synthetic gene technologies in zebrafish, creating new avenues by which to explore dynamic mRNA changes in a variety of cardiac disease models.