Manu grew up in Antwerp, Belgium, where he completed his PhD on ‘Macrovascular Endothelial Heterogeneity’ and the ‘Therapeutic potential of MAPC to treat lymphedema’ under the mentorship of Aernout Luttun, PhD at the University of Leuven. In 2014, Manu joined the MacRae lab as a postdoc, working on diverse academic and industrial projects primarily focused on modeling cardiac disease in zebrafish and high-throughput screening mechanisms to expedite drug discovery for heart failure. Since 2018, Manu is a junior faculty member at the Brigham and Women’s Hospital and acts as the lab director of the MacRae lab. His research now primarily focuses on understanding the genetic and epigenetic mechanisms in arterial development and disease using both in vivo and in vitro models. In his spare time, Manu likes to play soccer, make an attempt at a decent golf shot and enjoys a good IPA.