Ashmita KC

After completing my undergraduate studies at Simmons University in Boston, I joined the Macrae lab in 2019 as a research assistant working with Dr. Kiviniemi. Our current work focuses on characterizing molecular and functional phenotypes in zebrafish model for various genetic loci that have been associated with atrial fibrillation (AF). We are interested in understanding how these genetic predispositions affect the interaction between molecular markers that are crucial for cardiac structural and electrical integrity and how it affects the overall planar cell polarity (PCP) pathway. The goal of our project is to better understand the mechanistic pathway that interconnects genetic defects to atrial fibrillation.